The DNA Splicers are located inside the Gnarled Den. But the Splicers are hidden, so you will need to equip the Dowsing Machine to find their precise location.
You can find the Gnarled Den on the west side of Mt. Chimney. It can only be accessed while Soaring with Latios or Latias, and it will only appear if you have both Reshiram (Omega Ruby) and Zekrom (Alpha Sapphire) in your party.
You can use the DNA Splicers to fuse Kyurem with either Reshiram or Zekrom.
Before you gain access to the Gnarled Den, you must first catch Reshiram (Omega Ruby) and Zekrom (Alpha Sapphire).
They can be found in the Fabled Cave, which is only accessible through Soaring.
Note: Each of Reshiram & Zekrom are exclusive to their respective versions. So you will need to get the other one via trading or with cheats. Having both Pokémon in your team is a requirement for the Gnarled Den to appear.
To unlock the Fabled Cave on the east of Route 110 and encounter Reshiram or Zekrom, you must first accomplish the following:
- Defeat Primal Groudon (Omega Ruby) or Primal Kyogre (Alpha Sapphire)
- Raise a Pokémon to Level 100 in your team
Once you have both of those objectives done, the Gnarled Den will become accessible.
DNA Splicers Location (Step-by-Step)
You can find the Gnarled Den on the west side of Mt. Chimney while Soaring with Latios or Latias using the Eon Flute. And once you’re in the correct area, you will also need to equip the Dowsing Machine to find the DNA Splicers in the northwest corner of the cave.
Note: You can also find the portal to encounter Kyurem in the northernmost part of the Gnarled Den.
With both Reshiram and Zekrom in your party, here’s the step-by-step process of how to get your DNA Splicers.
Step 1: Fly to Mt. Chimney. From here, use the Eon Flute to Soar.
Step 2: While Soaring, head directly west until you find the Gnarled Den.
You can find the Gnarled Den in the exact location below:
Step 3: After landing at the Gnarled Den, go north towards the cave, then head inside.
Step 4: Once inside, equip the Dowsing Machine and go north.
Step 5: Go as far north as you can, then at the end just turn west towards the corner. This is where you’ll find the DNA Splicers.
Keep walking around this corner until you land on the exact spot. Once the Dowsing Machine glows red, you’ll be able to pick up the DNA Splicers.
What Do the DNA Splicers Do?
You can use the DNA Splicers on Kyurem to fuse with either Reshiram or Zekrom to get White Kyurem or Black Kyurem, respectively. You can also reverse this process at any time by using the DNA Splicers again on Kyurem’s fused form.
Note: You can only have one of Kyurem’s fused forms present at a time.
Fusing Kyurem with Reshiram or Zekrom
Step 1: Select the DNA Splicers from your Key Items. When prompted, select Kyurem from your team to use the item on.
Step 2: Select Reshiram or Zekrom to fuse with Kyurem. You’ll also need one of them in your team to do this (not in the PC).
After that, you’ll be all set.
Reshiram or Zekrom will disappear once fused with Kyurem.
Note that Kyurem’s forms also have their own signature moves:
- White Kyurem can learn the moves Ice Burn and Fusion Flare.
- Black Kyurem can learn the moves Freeze Shock and Fusion Bolt.